연구활동 Research activities

논문
  • [국외]
  • NMR metabolomics analysis of Escherichia coli cells treated with Turkish propolis water extract reveals nucleic acid metabolism as the major target, Journal Of Applied Microbiology (2023)
  • Identification of interaction partners using protein aggregation and NMR spectroscopy, PLOS ONE 17 (2022)
  • A simple and sensitive detection of the binding ligands by using the receptor aggregation and NMR spectroscopy: a test case of the maltose binding protein., Journal Of Biomolecular Nmr 75 (2021)
  • Development of an Autoinducible Plasmid for Recombinant Protein Production, Protein and Peptide Letters 28 (2021)
  • Relationship between recombinant protein expression and host metabolome as determined by two-dimensional NMR spectroscopy, Plos One 12 (2017)
  • Application of NMR Spectroscopy in the Assessment of Radiation Dose in Human Primary Cells, Chemistry & Biodiversity 12 (2015)
  • Probing Metabolite Space of Escherichia coli via Growth Medium Composition as Monitored by Two-Dimensional NMR Spectroscopy, Chemistry & Biodiversity 12 (2015)
  • Amphiphilic Thiol Functional Linker Mediated Sustainable Anti-Biofouling Ultrafiltration Nanocomposite Comprising a Silver Nanoparticles and Poly(vinylidene fluoride) Membrane, Acs Applied Materials & Interfaces 5 (2013)
  • Application of Two-Dimensional NMR Spectroscopy to Metabotyping Laboratory Escherichia coli Strains, Chemistry & Biodiversity 10 (2013)
  • Stress adaptation of Saccharomyces cerevisiae as monitored via metabolites using two-dimensional NMR spectroscopy, FEMS YEAST RESEARCH 12 (2012)
  • Recombinant Production, Isotope Labeling and Purification of ENOD40B: A Plant Peptide Hormone, PROTEIN AND PEPTIDE LETTERS 19 (2012)
  • The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements, EUROPEAN JOURNAL OF PHARMACOLOGY 682 (2012)
  • A simple NMR method to measure crosslink density of natural rubbercomposite, Polymer testing 29 (2010)
  • Stationary Phase Expression, Purification, and Characterization of XorKI, a Restriction Endonuclease from Xanthomonas oryzae pv. oryzae, PROTEIN AND PEPTIDE LETTERS 17-3 (2010)
  • Recombinant expression, purification, and characterization of XorKII: a restriction endonuclease from Xanthomonas oryzae pv. oryzae., Protein Expression and Purification 62-2 (2008)
  • Reevaluating the capability of Taq DNA polymerase: Long PCR amplification, PROTEIN AND PEPTIDE LETTERS 14-4 (2007)
  • Recombinant expression, isotope labeling, refolding, and purification of an antimicrobial peptide, piscidin, PROTEIN EXPRESSION AND PURIFICATION 51-2 (2007)
  • Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex., J Biol Chem 280-31 (2005)
  • (1)H, (15)N and (13)C Resonance Assignments of a Protein Involved in the Autophagy Process, At4g21980.1 from Arabidopsis thaliana., J Biomol NMR. 32-4 (2005)
  • The native metastability and misfolding of serine protease inhibitors., Protein Pept Lett. 12-5 (2005)
  • Degradation of wild-type alpha-synuclein by a molecular chaperone leads to reduced aggregate formation., Cell Biochem Funct. 23(2) (2005)

  •  
  • [국내]
  • H-1, C-13, and N-15 resonance assignments of ENOD40B, a plant peptide hormone, Journal Of The Korean Magnetic Resonance Society (2023)
  • Comparison of Three Different Entry Molecules for Probing a Metabolic Response to Radiation Exposure byTwo-Dimensional NMRSpectroscopy, Bulletin of the Korean Chemical Society 41 (2020)
  • Relationship between Protein Expression Pattern and Host Metabolome Perturbation as Monitored by Two-Dimensional NMR Spectroscopy, BULLETIN OF THE KOREAN CHEMICAL SOCIETY 40 (2019)
  • Stress Adaptation of Escherichia coli as Monitored via Metabolites by Using Two-Dimensional NMR Spectroscopy, Journal of the Korean Magnetic Resonance Society 21 (2017)
  • Discrimination of Rice Products by Geographical Origins and Cultivars by Two-Dimensional NMR Spectroscopy, Bulletin Of The Korean Chemical Society 37 (2016)
  • Application of NMR Spectroscopy to Assessment of Radiation Dose and Time Lapse, Bulletin Of The Korean Chemical Society 36 (2015)
  • Searching for Growth Conditions for Optimized Expression of Recombinant Proteins in Escherichia coli by Using Two-Dimensional NMR Spectroscopy, Bulletin Of The Korean Chemical Society 36 (2015)
  • Dosage Effects of Salt and pH Stresses on Saccharomyces cerevisiae as Monitored via Metabolites by Using Two Dimensional NMR Spectroscopy, BULLETIN OF THE KOREAN CHEMICAL SOCIETY 34 (2013)
  • Tracing Metabolite Footsteps of Escherichia coli Along the Time Course of Recombinant Protein Expression by Two-Dimensional NMR Spectroscopy, BULLETIN OF THE KOREAN CHEMICAL SOCIETY 33 (2012)
  • Recombinant Expression, Isotope Labeling and Purification of the Vitamin D Receptor Binding Peptide , BULLETIN OF THE KOREAN CHEMICAL SOCIETY 32-12 (2011)
  • Metabolic Profiling of Urine Samples from Colorectal Cancer PatientsBefore and After Surgical Treatments, Journal of the Korean Magnetic Resonance Society 14 (2010)
  • Discovery of Novel Human Phenylethanolamine N-methyltransferase (hPNMT) Inhibitors Using 3D Pharmacophore-Based in silico, Biophysical Screening and Enzymatic Activity Assays, MOLECULES AND CELLS 29-6 (2010)
  • Combining Information of Common Metabolites Reveals Global Differences between Colorectal Cancerous and Normal Tissues, BULLETIN OF THE KOREAN CHEMICAL SOCIETY 31-2 (2010)
  • Comparison of Spectral Data of Metabolites Collected from Bruker and Varian 600 MHz Spectrometers, 한국자기공명학회 13-1 (2009)
  • Recombinant Expression and Purification of Cytoplasmic Domain of Syndecan-2 Proteoglycan, Bull. Korean Chem. Soc 29-12 (2008)
  • Ubiquitin fusion system for recombinant peptide expression and purification: Application to the cytoplasmic domain of syndecan-4, BULLETIN OF THE KOREAN CHEMICAL SOCIETY 28-9 (2007)
  • Recombinant expression and purification of functional XorII, a restriction endonuclease from Xanthomonas oryzae pv. oryzae, JOURNAL OF MICROBIOLOGY 45-2 (2007)
  • Expression and Purification of a Cathelicidin-Derived Antimicrobial Peptide, CRAMP, J. Microbiol. Biotechnol. 16-9 (2006)
  • NMR Structural Analysis and 3D Homology Modelling of APG8a from Arabidopsis thaliana, Journal of the Korean Magnetic Resonance Society 10-1 (2006)
특허
  • [국내]
  • 엘라스틴 유사 폴리펩타이드 융합 단백질에 기초한 응집 분산 크로마토그래피, 2024-02 (출원)
  • 독성 단백질 생산용 재조합 플라스미드, 2022-03 (출원)
  • 자동유도 플라스미드, 2021-07 (등록)
  • 자동유도 플라스미드, 2020-03 (출원)
  • 자동유도 플라스미드, 2019-05 (출원)
  • TVMV 프로테아제 대량 생산용 벡터 및 이를 이용한 TVMV 프로테아제 대량 생산 방법, 2018-11 (등록)
  • ELP 융합 단백질을 이용한 결합세기 판별방법, 2018-10 (출원)
  • TVMV 프로테아제 대량 생산용 벡터 및 이를 이용한 TVMV 프로테아제 대량 생산 방법, 2017-02 (출원)
  • 제한효소의 생산방법, 2013-01 (등록)
  • 고분자의 가교밀도 측정방법 및 노화정도 측정방법, 2012-12 (등록)
  • ＨＳＱＣ ＮＭＲ을 이용한 대사물질 정량 분석 방법, 2011-11 (등록)
  • 고분자의 가교밀도 측정방법 및 노화정도 측정방법, 2010-07 (출원)
  • 혼합기능을 갖는 신축성 플라스틱 용기, 2009-12 (출원)
  • 건물일조권보호를 위한 일조량 조절장치, 2009-08 (출원)
  • HSQC NMR을 이용한 대사물질 정량 분석 방법, 2009-06 (출원)
  • 제한효소의 생산방법, 2009-02 (출원)
  • 잔토모나스속 균주의 엔도뉴클레아제인 XorI의 발현 및 정제 방법, 2006-03 (출원)
  • 잔토모나스속 균주의 엔도뉴클레아제인 XorII의 발현 및 정제 방법, 2006-03 (출원)
저역서
  • 줌달의 기본일반화학, 2020-12
  • (레이먼드 창의) 일반화학, 2020-03
  • (레이먼드 창의) 기본 일반화학, 2020-03
  • (바우어의) 대학화학기초, 2020-03
  • (레이먼드 창의) 일반화학, 2018-03
  • 대학화학의 기초, 2017-01
  • (줌달의) 기본 일반화학, 2016-03
  • 일반화학, 2016-02
  • 기본 일반화학 : 레이먼드 창, 2015-02
  • 일반화학, 2013-02
  • (Bauer) 일반화학, 2012-03
  • (Silberberg) 일반화학., 2012-03
  • 줌달의 일반화학, 2010-03
  • 일반화학 (Brady), 2010-03
  • 레이먼드창의 일반화학, 2010-03
  • 공학도를 위한 일반화학, 2009-02
학술발표
  • Harnessing elastin-like polypeptides for fast protein-protein interaction discovery, 제55회 총회 및 하계 학술대회(한국자기공명학회), 2023-06
  • NMR analysis of protein-protein interactions using ELPs with reversible aggregation in response to temperature changes, 제55회 총회 및 하계 학술대회(한국자기공명학회), 2023-06
  • The New Protein-Protein interaction Search Method: Rapid Interacting Molecular Screening (RIMS), 제130회 대한화학회 학술발표회 총회 및 기기전시회(대한화학회), 2022-10
  • Identifying Protein-Protein Interaction Utilizing Unique Behavior of Elastin-Like Polypeptide (ELP), 제130회 대한화학회 학술발표회 총회 및 기기전시회(대한화학회), 2022-10
  • Introducing a New Technique for Identifying Protein-Protein Interaction: Aggregate-Pulldown, 2022 한국자기공명학회 제54회 총회 및 학술발표회(한국자기공명학회), 2022-06
  • Identifying protein-protein interaction based on NMR signal disappearance and restoration, 2022 한국자기공명학회 제54회 총회 및 학술발표회(한국자기공명학회), 2022-06
  • NMR‐based metabolomics analysis of Escherichia coli cells exposed to water extract of Turkish propolis, Metabolomics 2021(Metabolomics Society), 2021-06
  • An Autoinducible Plasmid Equipped with a Stationary Phase Promoter for Recombinant Protein Production, EXPERIMENTAL BIOLOGY 2021(ASBMB), 2021-04
  • An Alternative Production of Recombinant Proteins Containing Disulfide Bonds in E. coli, 127th General Meeting of the Korean Chemical Society(대한화학회), 2021-04
  • Ligand Screening by Using Supramolecular Protein Complex and NMR Spectroscopy, 62nd ENC(ENC), 2021-03
  • Auto-Inducible Stationary Phase Promoter (SPP) for Recombinant Protein Production, 제125회대한화학회 학술발표회 및 총회(대한화학회), 2020-07
  • Methodology development of ligand screening by using NMR spectroscopy, 124회 대한화학회 학술발표회 총회 및 기기전시회 안내(대한화학회), 2019-10
  • Analyzing Turkish Propolis from a variety of Geographical Origins by Using NMR Spectroscopy, 124회 대한화학회 학술발표회 총회 및 기기전시회 안내(대한화학회), 2019-10
  • Investigation of propolis from various origins in Turkey, Euroanalysis-2019(European Chemical Society), 2019-09
  • Qualitative analysis of Turkish propolis from various geometric origins by using NMR spectroscopy, 2019년 한국자기공명학회 하계 학술대회(한국자기공명학회), 2019-06
  • Screening weakly binding ligands by using NMR spectroscopy, 2019년 한국자기공명학회 하계 학술대회(한국자기공명학회), 2019-06
  • Methodology Development of Screening Weak Binders by Using NMR Spectroscopy, 123회 대한화학회 학술발표회 총회 및 기기전시회 안내(대한화학회), 2019-04
  • Construction of Auto-Inducible Promoters for Recombinant Protein Production, 123회 대한화학회 학술발표회 총회 및 기기전시회 안내(대한화학회), 2019-04
  • Application of the Red Fluorescent Protein as an Indicator of Recombinant Protein Production in Escherichia coli, 대한화학회 제122회 학술발표회(대한화학회), 2018-10
  • Screening of Weak Binders Using Protein Supramolecular Complex, 제50회 총회 및 하계 학술발표회(한국자기공명학회), 2018-06
  • Ligand Screening Methodology Development Based on Protein Supramolecular Complex and NMR Metabolomics, 대한화학회 제121회 학술발표회(대한화학회), 2018-04
  • Assessment of Radiation Exposure and Time Lapse by 2D NMR-based Metabolite Profiling: 13C-Pyruvate Labeling of Metabolites in Human Umbilical Vein Endothelial Cells, 대한화학회 제119회 총회 및 학술발표회(대한화학회), 2017-04
  • Recombinant Protein Expression Patterns vs. Metabolite Profiles Under NaCl Stresses as Investigated by Two-Dimensional NMR Spectroscopy, 한국대사체학회정기학술대회(한국대사체학회), 2017-04
  • Recombinant Protein Expression Patterns vs. Metabolite Profilesby Two-Dimensional NMR Spectroscopy, International Symposium of Federation of Korean Societies for Molecular & Biomedical Sciences 2016(한국자기공명학회, 한국단백질학회, 한국생물물리학회), 2016-06
  • Searching for a Relationship between Protein Expression and Metabolic Profiles by Using Two-Dimensional NMR Spectroscopy, 제47회 총회 및 학술발표회(한국자기공명학회), 2015-11
  • Diffusion of input metabolites as monitored by 1H-13C HSQC experiments, 제46회 총회 및 동계 학술발표회(한국자기공명학회), 2015-02
  • Profiling rice metabolites by two dimensional NMR spectroscopy, 한국자기공명학회 제45회 총회 및 하계 학술발표회(한국자기공명학회), 2014-07
  • Metabolite profiling by 1H-13C HSQC spectroscopy, 한국대사체학회 제2회 정기총회 및 학술대회(한국대사체학회), 2014-04
  • Probing Metabolite Space for Optimized Expression of Recombinant Proteins inEscherichia coli by Using Two-Dimensional NMR Spectroscopy, 한국자기공명학회 제44회 총회 및 동계 학술발표회(한국자기공명학회), 2014-02
  • Medium Dependence of Escherichia coli Intracellular Metabolites as Observed by TwoDimensional NMR Spectroscopy, 한국자기공명학회 제44회 총회 및 동계 학술발표회(한국자기공명학회), 2014-02
  • Metabolite profiling by two-dimensional NMR spectroscopy, 한국자기공명학회 제44회 총회 및 동계 학술발표회(한국자기공명학회), 2014-02
  • Dosage Effect of Stresses on Saccharomyces cerevisiae Explored by Two-Dimensional NMR Spectroscopy, 한국자기공명학회 제43회 총회 및 하계 학술발표회(한국자기공명학회), 2013-07
  • Metabotyping Laboratory Escherichia coli Strains by Two-Dimensional NMR Spectroscopy, 한국자기공명학회 제42회 총회 및 동계 학술발표회(한국자기공명학회), 2013-02
  • Metabolite Profiling of Laboratory Escherichia coli Strain by Two-Dimensional NMR Spectroscopy, Frontiers of NMR in Biology(Keystone Symposia), 2013-01
  • Exploration of Innerspace of Rubber by NMR, 한국자기공명학회 제41회 총회 및 20주년 기념 국제학술대회(한국자기공명학회), 2012-06
  • Liver Metabolite Profiling of Wildtype and Knockout Mutant of the Mouse Sigma-1 Receptor, 한국자기공명학회 제41회 총회 및 20주년 기념 국제학술대회(한국자기공명학회), 2012-06
  • Salt and pH Stress Adaptation of Saccharomyces cerevisiae as Monitored via Metabolites by Using Two Dimensional NMR Spectroscopy, 한국자기공명학회 제41회 총회 및 20주년 기념 국제학술대회(한국자기공명학회), 2012-06
  • Isotope Labeling and Purification of a Regulatory Peptide of the Vitamin D Receptor by Recombinant DNA Technology, 한국자기공명학회 제41회 총회 및 20주년 기념 국제학술대회(한국자기공명학회), 2012-06
  • Metabolite Profiling during the Recombinant Protein Expression as Monitored by Two-Dimensional NMR Spectroscopy, 한국자기공명학회 제40회 총회 및 동계 학술발표회(한국자기공명학회), 2012-02
  • Metabolite Profiling of Saccharomyces cerevisiae under Various Stress Conditions, 대한화학회 제108회 총회 및 학술발표회, 2011-09
  • Recombinant Expression, Isotope Labeling and Purification of a Regulatory Peptide of the Vitamin D Receptor, 한국자기공명학회 제39회 총회 및 하계 학술발표회, 2011-08
  • Metabotyping of pH Stress Adaptation of Saccharomyces cerevisiae as Monitored by 2 dimensional NMR Spectroscopy, 대한화학회 제107회 총회 및 학술발표회, 2011-04
  • NMR Exploration of Innerspace of Rubber, 한국자기공명학회 제38회 총회 및 동계 학술발표회, 2011-02
  • Stress Adaptation of Saccharomyces cerevisiae as Monitored by Metabolites, 한국자기공명학회 제38회 총회 및 동계 학술발표회, 2011-02
  • Metabolic Profiling of Saccharomyces Cerevisiae under Various Stress Conditions, 한국자기공명학회 제37회 학술발표회, 2010-06
  • Urinary Metabolic Profiling of Colorectal Cancer Patients, 한국자기공명학회, 2010-02
  • Metabolomics by 2D NMR, 2009 Bruker Users' Meeting, 2009-07
  • 2D NMR을 이용한 대사체 정량분석, 2009 한국자기공명학회 Solution NMR Workshop, 2009-05
  • Metabolic profiling by two dimensional heteronuclear NMR spectroscopy, 대한화학회 103회 총회 및 학술발표회, 2009-04
  • 용매와 NMR을 사용한 고무의 가교밀도 탐색, 한국고무학회, 2009-03
  • Comparison of spectral data of metabolites collected from 600MHz spectrometers from two major manufacturers, 한국자기공명학회 제 34회 학술발표회, 2009-02
  • Recombinant expression, purification, and biochemical characterization of functional XorI from Xanthomonas oryzae pv. oryzae, KSBMB, 2006-05
  • Recombinant expression and purification of antibacterial peptide, piscidin, 한국펩타이드학회, 2005-12
  • Recombinant expression and purification of antibacterial peptide, piscidin, 대한화학회, 2005-10
  • Recombinant expression and purification of functional XorI and XorII from Xanthomonas oryzae pv. oryzae (Xoo), 대한화학회, 2005-10
  • Recombinant expression and purification of antibacterial peptide, Piscidin, 한국생화학분자생물학회, 2005-05
  • Backbone assignments and secondary structure prediction of APG8a from Arabidopsis thalinana, 한국생화학분자생물학회, 2005-05
  • Expression and NMR studies of a cathelicidin-derived antimicrobial peptide, CRAMP, 한국생화학분자생물학회, 2005-05
  • Recombinant expression, purification, and in vitro refolding of the small ubiquitin-like modifiers (SUMO) from Arabidopsis thaliana, 한국생화학분자생물학회, 2005-05